Gene therapy for lung cancer and mesothelioma - Thomas L. Petty 39th Annual Aspen Lung Conference: Genes and Gene Therapy
Chest - June 1, 1997, by Steven M. Albelda
The idea using of gene therapy began with the straight-forward paradigm of treating genetic diseases in which one gene was missing. Although this strategy seems conceptually simple, it has proved to be difficult to implement in practice because the vectors currently avai... (Read More)
ALFACELL initiates Phase III clinical trial for asbestos-related cancer
Business Wire - May 15, 1997
BLOOMFIELD, N.J.--(BUSINESS WIRE)--May 15, 1997--
Phase II Interim Analysis Presented at the 4th International
Mesothelioma Conference
ALFACELL Corp. (NASDAQ: ACEL) presented today an update of its on-going Phase II clinical trial of its flagship product, ON... (Read More)
Asbestos-related disorders: a realistic perspective
Chest - May 1, 1997, by David M. Rosenberg
(CHEST 1997; 111:1424-26)
Millions of workers have had occupational exposure to asbestos throughout the last century. While the literature is replete with descriptions of asbestos-related disorders, it is difficult to accurately determine current prevalence and incidence... (Read More)
Surgically treated pneumothorax: radiologic and pathologic findings
Chest - February 1, 1997, by Kirk G. Jordan,
J. Stephen Kwong,
Julia Flint,
Nestor L. Muller
Spontaneous pneumothorax can be divided into primary and secondary groups. Primary spontaneous pneumothorax (PSP) or idiopathic spontaneous pneumothorax results from rupture of small apical blebs or bullae. This etiology for PSP is best supported by data reported by Bar... (Read More)
The role of cytologic evaluation of pleural fluid in the diagnosis of malignant mesothelioma
Chest - January 1, 1997, by Andrew A. Renshaw,
Barbara R. Dean,
Karen H. Antman,
David J. Sugarbaker,
Edmund S. Cibas
Study objective: Treatment of malignant mesothelioma (MM) at an early stage results in increased survival. Cytologic examination of pleural effusions is one of the first diagnostic techniques attempted in these patients. The objective of this study was to define the role of... (Read More)
Thoracoscopic talc poudrage pleurodesis for malignant effusions: a review of 360 cases
Chest - December 1, 1996, by Jean-Regis Viallat,
Francoise Rey,
Philippe Astoul,
Christian Boutin
A Review of 360 Cases
Objective: To assess the efficacy, permanence, and safety of thoracoscopic talc poudrage (TTP) for pleurodesis in malignant effusions. Design: Retrospective. Participants: Patients with lifetime foflow-up who received TTP in two related centers in... (Read More)
Unilateral pleural thickening
Chest - November 1, 1996, by George H. Lum,
Ronald K. Poropatich
A 32-year-old African-American man with a prior diagnosis of biopsy-proven sarcoidosis presented in July, 1994, with a complaint of increasing dyspnea on exertion, decreased exercise tolerance, and a mild nonproductive cough over the preceding 3 months. His original diagn... (Read More)
Vegetables, fruit, and cancer prevention: a review
Journal of the American Dietetic Association - October 1, 1996, by Kristi A. Steinmetz,
John D. Potter
Historically, consumption of particular fruits and vegetables was thought to prevent or cure ailments ranging from headaches to heart disease. In fact, early medicine revolved largely around the prescription of specific food concoctions (plant foods in particular) for certa... (Read More)
Alfacell begins new clinical trial in pancreatic cancer; Study to compare its ONCONASE + tamoxifen vs. GEMZAR
Business Wire - August 20, 1996
BLOOMFIELD, N.J.--(BUSINESS WIRE)--Aug. 20, 1996--Alfacell Corp. (OTCBB:ACEL) announced today that it has begun a new Phase III multi-center, randomized trial comparing its novel cancer therapeutic ONCONASE(R) used in combination with tamoxifen to GEMZAR(R) in patients... (Read More)
Extensive pulmonary metastases in malignant pleural mesothelioma: a rare clinical and radiographic presentation
Chest - July 1, 1996, by Nobuya Ohishi,
Teruaki Oka,
Toshiaki Fukuhara,
Hideki Yotsumoto,
Yoshio Yazaki
A Rare Clinical Presentation and Radiographic
We report a case of malignant pleural mesothelioma in a patient who presented with pleural effusion and reticulonodular shadow on chest radiograph. Pulmonary metastases were diagnosed by transbronchial lung biopsy specimen ... (Read More)
Cancer occurrence and screening in family practice: a 20-year experience
Journal of Family Practice - July 1, 1996, by Gerard N. Kiernan,
Paul S. Frame
Background. This article is a sequel to a previously published article describing the occurrence of cancer in a rural family practice and the contribution of screening to the diagnosis of breast, colorectal, and cervical cancer. Together, the two articles describe a 20-year... (Read More)
Intrapericardial minocycline sclerosis for malignant pericardial effusion
Chest - June 1, 1996, by Ilan Lashevsky,
Rami Ben Yosef,
Diana Rinkevich,
Shimon Reisner,
Walter Markiewicz
Study objective: To evaluate the effectiveness and safety of minocycline hydrochloride (minocycline) intrapericardially in patients with malignant pericardial effusion.
Design: Consecutive patients admitted to the hospital during a 32-month period received intra-pericardial... (Read More)
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