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Alfacell stock commences trading on The Nasdaq Stock Market

Business Wire - December 5, 1996

BLOOMFIELD, N.J.--(BUSINESS WIRE)--Dec. 5, 1996--Alfacell Corp. (NASDAQ:ACEL) announced today that its common stock has commenced trading on the NASDAQ SmallCap Market Securities system beginning today under the symbol "ACEL."

The NASDAQ Stock Market is a major national and international stock market that uses computers and telecommunications networks for the trading and surveillance of thousands of securities.

Alfacell, a leader in the area of ribonuclease (RNase) research, is currently testing its flagship anticancer drug ONCONASE(R) in various clinical trials. Developed by Alfacell scientists, ONCONASE is a novel RNase protein used in the investigational treatment of patients with solid tumors, most of which are resistant to other chemotherapeutic drugs.

ONCONASE, the only cytotoxic RNase currently in clinical trials, has been used in the treatment of patients with a variety of solid tumors and has demonstrated in vitro and in vivo activity in multiple-drug resistant (MDR) tumor models. MDR is thought to be responsible for approximately 90% of chemotherapy failures.

The company is currently conducting multi-center Phase III clinical trials in advanced pancreatic cancer patients, a multi-center Phase II trial in patients with malignant mesothelioma and pilot studies in renal cell carcinoma and prostate cancer.

Alfacell, a biopharmaceutical company located in Bloomfield, N.J., is engaged primarily in the research and development of novel ribonuclease enzymes for various therapeutic applications.

CONTACT: Alfacell Corp.

Donna Brasko, 201/748-8082

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